MEA Parser
PEIJ, member of the HESI Cardiac Safety Committee Myocyte Database Subteam, released "MEA Parser" which converts the imported raw data of various MEA equipment (MED64, Maestro and MCS) into common binary data on the Windows (stand-alone and do not need a connection to the network), supported by AMED, so that it can be used internationally in research for in vitro drug effects on human iPSc derived cardiomyocytes.
MEA Parser makes sense to store not only processed data but also raw data in the database for verification and open science.
Every researcher using MED64/Maestro/MCS can access converted common binary data, and waveform analysis can be carried out with their own filter and wave analysis tools.
Researchers can develop new endpoints in the international open science context.
[Present a proposal for international standardization of a method for evaluating drug cardiotoxicity using iPS cell technology]
In Japan, "Present a proposal for international standardization of a method for evaluating drug cardiotoxicity using iPS cell technology" is a goal to be achieved by around 2020 in the Healthcare Policy (Approved by Cabinet on July 22, 2014, Partial change on February 17, 2017). PEIJ published a paper on our "MEA Parser" that shows the usefulness of the raw data of various MEA devices (Inutsuka T. The role of the “MEA Parser”: International release and perspectives. Curr Study Environ Med Sci 10.). PEIJ also reported to AMED that PEIJ could suggest storage of the raw data in the database in international standardization of the database.
